Spangsberg is self-taught, with drawing as the only formal training. She has within a few years created a distinctive body of abstract paintings and one-line drawings exhibited in sold out solo shows in Copenhagen (2019), Paris (2018), Sydney (2017), London (2017) and New York (2017). Her work has been featured in magazines such as Unconditional Magazine and Vogue, and she has collaborated with labels like Matteau Swim and Maison Balzac (2016). She was chosen to create the 40 edition poster for Copenhagen Jazz Festival in 2018.